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Guotai Junan's annual strategy for innovative drugs in 2025: innovative pharmaceutical companies have accelerated into the harvest period, and the valuation has been at a historical low in the past five years. Guotai Junan said that the centralized purchasing policy has become stable, mature and normalized, and the marginal impact has weakened. Innovative drugs have gained policy inclination in the medical insurance negotiation. In the past two years, the policy has continued to promote pharmaceutical innovation, and the top-level design and local supporting chain support the development of innovative drugs. Commercial insurance is expected to bring new growth momentum to China's pharmaceutical market, and the overall industry trend is upward. At present, the trend of innovative drug industry is improving, the supply continues to accelerate, and a number of domestic innovative drugs are approved soon, which is expected to drive a new round of heavy volume. At the same time, the commercialization has achieved remarkable results and has occupied a dominant position in some sub-sectors. Pharma's performance continued to differentiate, and innovative drugs and just-needed drugs performed well. Biotech commercialization continues to increase, per capita yield continues to increase, the node of turning losses is approaching, and innovation ushers in the harvest period. Horizontal comparison: compared with overseas peers, the overall valuation of domestic innovative pharmaceutical companies is in a historically low range; Vertical comparison: the valuation of SW- pharmaceutical biology and SW- chemical preparations is at a historical low in the past five years, and it is expected that the valuation of subsequent sectors will pick up.Lian Ping, president of the Chief Industry Research Institute of Guangkai, believes that it is expected to reduce the RRR by about 100 basis points in 2025, releasing more than 3 trillion yuan of liquidity. Among them, there is limited room for reducing the deposit reserve ratio of small and medium-sized financial institutions, and the expected RRR reduction is about 50 basis points.Trump appointed TOM BARRACK as the US ambassador to Turkey.

Syrian opposition forces claimed to have taken control of the eastern Syrian city of Deir ez-Zor. According to Al Jazeera and Arabiya TV, on the 10th local time, Hassan Abdel Ghani, commander of Syrian opposition forces, said that "the eastern Syrian city of Deir ez-Zor has been completely controlled".Lian Ping, president of the Chief Industry Research Institute of Guangkai, believes that it is expected to reduce the RRR by about 100 basis points in 2025, releasing more than 3 trillion yuan of liquidity. Among them, there is limited room for reducing the deposit reserve ratio of small and medium-sized financial institutions, and the expected RRR reduction is about 50 basis points.More than 700 listed companies have announced the replacement of the audit institutions in 2024. According to incomplete statistics, since the beginning of this year, the number of listed companies planning to replace the accounting firms in 2024 has exceeded 700. Among them, the number of listed companies that intend to change accounting firms in October and November is 248 and 200 respectively. Looking back at the "exchange tide", three phenomena stand out: First, in order to improve the quality and ability of capital market intermediaries, the supervision of accounting firms by the regulatory authorities has been significantly enhanced. Based on the principle of prudence, listed companies collectively cancel the contract with the "problem institute"; Second, under the heavy penalty, more and more accountants choose to change their firms to practice, while listed companies choose to change their firms instead of accountants; Third, listed companies employ audit institutions through competitive negotiation, public bidding, invitation bidding, etc. In the bidding process, in order to attract more customers and increase the signing rate, the phenomenon of audit institutions reducing prices has increased. (Securities Daily)

Australia's S&P/ASX200 index opened down 12.60 points, or 0.15%, at 8380.4 points on Wednesday, December 11th.Asian Development Bank: Reduce India's growth forecast from 7.0% to 6.5% in 2024 and from 7.2% to 7.0% in 2025.Ministry of Finance of Korea: Korea's financial market is still facing uncertainty.